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Nanotecnologie e rilascio di droghe

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  • First Common Gene Found For Congenital Heart ...
    L'esistenza del Reale Rischio Congenito di CAD, noto da anni, rappresenta l'aspetto biologico delle mutazioni genetiche scoperte recentemente ed è la ... Vai al commento

  • New Step In Protein Production Could Explain ...
    I find this paper really interesting, but not useful from clinical view point. As a matter of fact, General Practititoners need CLINICAL tool, reliabl... Vai al commento

  • Lack Of Energy-Regulating Gene Caused Mice To...
    To Genetics News From Medical News Today: Veritas Filia Temporis (Aulo Gello, II Century a. Ch) Since 30 years about I am unhearded emphasising that,.... Vai al commento

  • Consumer Information on: VIDAS fPSA rt Assay ...
    La diagnosi di cancro della prostata è clinica, a partire dal suo Reale Rischio CONGENITO. 1) Stagnaro-Neri M., Stagnaro S. Introduzione alla Semeioti... Vai al commento

Diagnosi
Complex disease: A global view of regulatory networks
Scritto da Nature Reviews: Genetics   
BiochimicaMarbach et al. have developed a novel resource of 394 human cell type- and tissue-specific gene regulatory networks, representing 146 different cell types, 111 tissues and 137 cell lines. Transcriptional regulatory circuits were inferred on the basis ... ...
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Technique: Unwanted sequences DASH off
Scritto da Nature Reviews: Genetics   
BiochimicaA new method called DASH (Depletion of Abundant Sequences by Hybridization) exploits the unique properties of the endonuclease Cas9 to target and prevent the amplification of unwanted sequences during next-generation sequencing (NGS) protocols, enabl ... ...
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Genetic testing: Whole-exome sequencing for clinical diagnostics
Scritto da Nature Reviews: Genetics   
BiochimicaA prospective study has found that singleton whole-exome sequencing (WES) as a first-tier test in infants with suspected monogenic genetic disorders outperforms standard care. The team compared the rate of diagnosis, clinical utility and impact on ma ... ...
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Development: A colourful map of cell fate
Scritto da Nature Reviews: Genetics   
BiochimicaResearchers have engineered a multicoloured zebrafish that produces skin cells in over 70 distinguishable colours, enabling tracking of the behavioural dynamics of hundreds of individual epithelial cells during skin regeneration in vivo.The transgeni ... ...
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Genetic testing: Clinical sequencing right on target
Scritto da Nature Reviews: Genetics   
BiochimicaAs genome sequencing moves from the research laboratory to the clinic, the accuracy of variant calls used in diagnoses is increasingly important. In a new study published in Genome Medicine, Goldfeder et al. reveal that many disease-associated genes ... ...
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Reprogramming: Your contacts reveal your past
Scritto da Nature Reviews: Genetics   
BiochimicaReprogramming differentiated cells into induced pluripotent stem cells (iPSCs) holds promise for generating patient-specific cells for regenerative medicine. However, transcriptomics and DNA-methylation analyses have revealed that iPSCs typically ret ... ...
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Gene regulation: Optical control of epigenetics
Scritto da Nature Reviews: Genetics   
BiochimicaReis et al. present chemo-optical modulation of epigenetically regulated transcription (COMET), a new conceptual approach that harnesses the strengths of small-molecule inhibitors and optogenetic techniques to control the epigenome using light.Pharma ... ...
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