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The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis
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Scritto da Human Reproduction - current issue |
 STUDY QUESTION
Is there an association between high levels of sperm DNA damage and miscarriage? SUMMARY ANSWER
Miscarriage rates are positively correlated with sperm DNA damage levels.
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The association between sperm sex chromosome disomy and semen concentration, motility and morphology
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Scritto da Human Reproduction - current issue |
 STUDY QUESTION
Is there an association between sex chromosome disomy and semen concentration, motility and morphology? SUMMARY ANSWER
Higher rates of XY disomy were associated with a significant increase ... ...
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Sperm vacuoles are linked to capacitation and acrosomal status
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Scritto da Human Reproduction - current issue |
 STUDY QUESTION
Is the presence of nuclear vacuoles really a negative parameter? SUMMARY ANSWER
As sperm vacuoles are associated with acrosomal and capacitation status, they appear to be a reflection of no ... ...
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Pravastatin does not prevent antiphospholipid antibody-mediated changes in human first trimester trophoblast function
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Scritto da Human Reproduction - current issue |
 STUDY QUESTION
What is the effect of pravastatin on antiphospholipid antibody (aPL) modulation of human first trimester trophoblast function? SUMMARY ANSWER
Pravastatin does not prevent the effects of aPL ... ...
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Soluble TRAIL is elevated in recurrent miscarriage and inhibits the in vitro adhesion and migration of HTR8 trophoblastic cells
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Scritto da Human Reproduction - current issue |
 STUDY QUESTION
What is the potential physiopathological role of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in recurrent miscarriage (RM), characterized by at least three consecutive pregnancy losses. ... ...
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Methylation profile of the promoters of Nanog and Oct4 in ICSI human embryos
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Scritto da Human Reproduction - current issue |
 STUDY QUESTION
What is the methylation status of the Nanog and Oct4 promoters in human gametes and ICSI embryos and is abnormal reprogramming of their methylation associated with developmental failure of ICSI embryos?
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Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis
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Scritto da Human Reproduction - current issue |
 BACKGROUND
Current non-invasive diagnostic methods for endometriosis lack sensitivity and specificity. In search for new diagnostic biomarkers for ovarian endometriosis, we used a hypothesis-generating targeted metabolomics approach ... ...
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