Endogenous Cushing's syndrome is a rare endocrine disorder that incurs significant cardiovascular morbidity and mortality, due to glucocorticoid excess. It comprises adrenal (20%) and non-adrenal (80%) aetiologies. While the majority of cases ar ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
The diagnosis of intraductal papillary lesions of the breast on core biopsy remains challenging in pathology, with most patients requiring formal surgical excision for a definitive diagnosis. The aim of this study was to determ ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
Histochemical staining of tissue is a fundamental technique in tissue diagnosis and research, but it suffers from significant variability. Efforts to address this include laboratory quality controls and quality assurance scheme ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
We hypothesised that CD1d expression in renal cell carcinoma (RCC) may play a role in modifying the host immune response. Our aims were to investigate the expression of CD1d and to correlate this with histopathology and clinica ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
To evaluate how the genetic and epigenetic profile of human papillomavirus 16 (HPV16) changes from asymptomatic cervical infections to cervical cancer (CaCx) development.
HPV16 physical statu ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
Assessing whether next-generation DNA sequencing (NGS) can be used to screen prostate cancer for multiple gene alterations in men routinely diagnosed with this disease and/or who are entered into clinical trials. Previous studi ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
There is high prevalence of hereditary haemochromatosis (HH) in North European populations, yet the diagnosis is often delayed or missed in primary care. Primary care physicians frequently request serum ferritin (SF) estimation ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
This cross-sectional study investigated the association between eight herpesviruses and the bacterial community profiles from the oral cavity of children with and without leukaemia.
Sixty par ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
Conventional methods for the identification of mycobacteria can be demanding and prolonged. Molecular methodologies, although rapid, are expensive and often exclusive to reference laboratories. Matrix-assisted laser desorption/ ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000
Near-tetraploidy/tetraploidy (NT/T) is a rare cytogenetic alteration in acute myeloid leukaemia (AML). NT/T-AML is categorised as complex cytogenetics and therefore, presumed to have an unfavourable prognosis. Our aim is to fur ... ...]]> [email protected] (Journal of Clinical Pathology ) Patologia clinica Tue, 03 Mar 2015 08:00:00 +0000