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Late-life deficits in cognitive, physical and emotional functions, childhood intelligence and occupational profile: a life-course examination of the Aberdeen 1936 Birth Cohort (ABC1936)
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Scritto da Age and Ageing |
Objectives: the ‘triad of impairment’ phenomenon describes the co-occurrence of age-related cognitive, emotional and physical functioning deficits. We investigated how occupational profile and childhood intelligence contribute ... ...
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Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study
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Scritto da Age and Ageing |
Background: delirium and dementia are common in the general hospital, being present in nearly 50% of older unselected admissions to hospital. Cognitive impairment is a risk factor for delirium, but the prevalence of previously undiagnosed ... ...
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Even a small change can make a big difference: the case of in-hospital cognitive decline and new IADL dependency
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Scritto da Age and Ageing |
Background: post-hospitalisation functional decline is a widely described phenomenon, yet factors related to new disability in instrumental activities of daily living (IADL) in previously independently functioning older adults are rarely s ... ...
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Diagnostic test accuracy of informant-based tools to diagnose dementia in older hospital patients with delirium: a prospective cohort study
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Scritto da Age and Ageing |
Background: delirium and dementia co-exist commonly in hospital. Older people with delirium have high rates of undiagnosed dementia, but delirium affects the use of cognitive testing in dementia diagnosis. Novel methods to detect dementia ... ...
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Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants
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Scritto da Age and Ageing |
Background: the apolipoprotein (APOE) e4 locus is a genetic risk factor for dementia. Carriers of the e4 allele may be more vulnerable to conditions that are independent risk factors for cognitive decline, such as cardiometabolic di ... ...
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Increasing delirium skills at the front door: results from a repeated survey on delirium knowledge and attitudes
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Scritto da Age and Ageing |
Background: delirium is under-recognised in comparison to other common and serious acute disorders. A 2006 survey of UK junior doctors (not undertaking specialist training) identified poor knowledge of the diagnostic criteria and treatment ... ...
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Education as protector against dementia, but what exactly do we mean by education
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Scritto da Age and Ageing |
Objectives: even though a great number of research studies have shown that high education has protective effects against dementia, some studies did not observe such a significant effect. In that respect, the aim of our study was to investi ... ...
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