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International cancer seminars: a focus on kidney cancer
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Scritto da Annals of Oncology - current issue |
Recent years have seen important advances in our understanding of the etiology, biology and genetics of kidney cancer. To summarize important achievements and identify prominent research questions that remain, a workshop was organized by IARC and ... ...
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ESMO consensus guidelines for the management of patients with metastatic colorectal cancer
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Scritto da Annals of Oncology - current issue |
Colorectal cancer (CRC) is one of the most common malignancies in Western countries. Over the last 20 years, and the last decade in particular, the clinical outcome for patients with metastatic CRC (mCRC) has improved greatly due not only to an i ... ...
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ESMO European Consortium Study on the availability, out-of-pocket costs and accessibility of antineoplastic medicines in Europe
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Scritto da Annals of Oncology - current issue |
 Background
The management of cancer is predicated on the availability and affordability of anticancer therapies, which may be either curative or noncurative. Aim
The primary aims of the study were to eval ... ...
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Consensus on precision medicine for metastatic cancers: a report from the MAP conference
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Scritto da Annals of Oncology - current issue |
Recent advances in biotechnologies have led to the development of multiplex genomic and proteomic analyses for clinical use. Nevertheless, guidelines are currently lacking to determine which molecular assays should be implemented in metastatic ca ... ...
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BRCA somatic mutations and epigenetic BRCA modifications in serous ovarian cancer
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Scritto da Annals of Oncology - current issue |
The significant activity of poly(ADP-ribose)polymerase (PARP) inhibitors in the treatment of germline BRCA mutation-associated ovarian cancer, which represents ~15% of HGS cases, has recently led to European Medicines Agency and food and d ... ...
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Challenging chemoresistant metastatic colorectal cancer: therapeutic strategies from the clinic and from the laboratory
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Scritto da Annals of Oncology - current issue |
As survival has improved for patients with metastatic colorectal cancer (mCRC), there is an increasing need for effective and well-tolerated third-line and subsequent-lines of treatment. Despite recent advances with the development of new-targete ... ...
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The impact of the revolution in hepatitis C treatment on hepatocellular carcinoma
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Scritto da Annals of Oncology - current issue |
Hepatitis C infection represents a global health problem affecting ~200 million chronically infected patients worldwide. Owing to the development of a fibrogenic and inflammatory micromilieu in the liver, hepatitis C virus (HCV)-infected patients ... ...
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