| Sequence of electrode implantation and outcome of deep brain stimulation for Parkinson's disease |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
 Introduction
The effect of the variability of electrode placement on outcomes after bilateral deep brain stimulation of subthalamic nucleus has not been sufficiently studied, especially with respect to the sequence of hemisphere imp ... ...
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| Incident impulse control disorder symptoms and dopamine transporter imaging in Parkinson disease |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
 Objective
To describe the incidence of, and clinical and neurobiological risk factors for, new-onset impulse control disorder (ICD) symptoms and related behaviours in early Parkinson disease (PD). Methods
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| The prediagnostic phase of Parkinson's disease |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
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The field of prediagnostic Parkinson's disease (PD) is fast moving with an expanding range of clinical and laboratory biomarkers, and multiple strategies seeking to discover those in the earliest stages or those ‘at risk’. It is wide ... ...
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| MRI characteristics of early PML-IRIS after natalizumab treatment in patients with MS |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
 Objective
The early detection of MRI findings suggestive of immune reconstitution inflammatory syndrome (IRIS) in natalizumab-associated progressive multifocal leukoencephalopathy (PML) is of crucial clinical relevance in terms of t ... ...
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| Extended interval dosing of natalizumab in multiple sclerosis |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
 Background
Natalizumab (NTZ), a monoclonal antibody to human α4β1/β7 integrin, is an effective therapy for multiple sclerosis (MS), albeit associated with progressive multifocal leuko ... ...
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| Progression of cognitive impairments in idiopathic REM sleep behaviour disorder |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
 Background
Idiopathic REM (rapid eye movement) sleep behaviour disorder (iRBD) has been implicated in cognitive impairments, but there is little evidence about progression of cognitive dysfunction in iRBD. Method ... ...
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| Antibodies to MOG and AQP4 in children with neuromyelitis optica and limited forms of the disease |
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Scritto da Journal of Neurology, Neurosurgery & Psychiatry current issue |
 Objective
To determine the frequency and clinical-radiological associations of antibodies to myelin oligodendrocyte glycoprotein (MOG) and aquaporin-4 (AQP4) in children presenting with neuromyelitis optica (NMO) and limited forms.
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