| Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity |
| Scritto da Nature Genetics |
 Adam Bass, Gad Getz and colleagues report whole-exome sequencing of 149 esophageal adenocarcinomas (EACs) and whole-genome sequencing of 15 EACs. They identify a mutational signature defined by a high prevalence of A>C transversions, as well as 26 genes mutated at high frequency in EACs.Fonte: Nature Genetics |